ESG risk score 37.21
Environmental score -
Social score -
Governance score -
ESG risk category High
Negligible Low Med High Severe
0-10 10-20 20-30 30-40 40+
Spruce Biosciences Inc
000.00
0.00 / 0.00%
00:00:00
52 week range
0000.00 000.00
Symbol SPRB:xnas
Currency USD
NASDAQ (Small cap)
Open Closed
15 minutes delayed
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Returns
Year to date (YTD) -35.25%
1 year 908.04%
3 years -66.28%
Data provided by 
Key stats
Price/earnings (LTM) -
Dividend yield (LTM) -
EPS (LTM) -52.72
Volatility (30 days) 116.08%
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Analyst consensus
Average rating Buy
Rating Analysts
Buy
5
Overweight
0
Hold
0
Underweight
0
Sell
0
Target price 186.6
Implied return 230.85%
Last updated 24-Apr-2026
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ESG risk
ESG risk is a measure of how well a company manages material ESG risks. Sustainalytics’ ESG risk category is designed to help investors identify and understand financially material ESG risks at the company level and how they might affect the long-term performance for equity investments. The scale is from 0-100. The lower the risk, the better (0 is equivalent to no risk and 100 the most severe).
Download ESG risk methodology (PDF)Data provided by 
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/ Financials
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About Spruce Biosciences Inc
Spruce Biosciences Inc is a late-stage biopharmaceutical company focused on developing and commercializing novel therapies for rare endocrine disorders with unmet medical needs. The company develops biologics and small-molecule product candidates aimed at addressing diseases with unmet medical needs and limited or no approved therapies. Its product candidate, TA-ERT for the treatment of Mucopolysaccharidosis Type IIIB (MPS IIIB), is a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase (rhNAGLU) intended as an enzyme replacement therapy for patients who lack rhNAGLU enzyme activity. TA-ERT is designed to restore rhNAGLU enzyme activity in the central nervous system following intracerebroventricular injection and promote clearance of heparan sulfate in the brain.
Sector Healthcare
Industry -
Market cap 0.152395056bn
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/ Frequently asked questions
You need to open and fund a Saxo account to buy Spruce Biosciences Inc stock. Once the account is approved, you can login to the platform (SaxoInvestor or SaxoTrader), search for Spruce Biosciences Inc (by name) or ‘APPL’ (by ticker), choose the number of shares you wish to buy, and place your order.
The ticker symbol for Spruce Biosciences Inc is SPRB:xnas. You can use this code to find the stock in our platforms and track its price and performance.
Spruce Biosciences Inc has its primary listing on NASDAQ (Small cap). You can trade Spruce Biosciences Inc with a Saxo account, alongside thousands of other stocks worldwide.
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